Reductive carboxylation is a major metabolic pathway in the retinal pigment epithelium

The retinal pigment epithelium (RPE) is a monolayer of pigmented cells that requires an active metabolism to maintain outer retinal homeostasis and compensate for oxidative stress. Using (13)C metabolic flux analysis in human RPE cells, we found that RPE has an exceptionally high capacity for reduct...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Du, Jianhai, Yanagida, Aya, Knight, Kaitlen, Engel, Abbi L., Vo, Anh Huan, Jankowski, Connor, Sadilek, Martin, Tran, Van Thi Bao, Manson, Megan A., Ramakrishnan, Aravind, Hurley, James B., Chao, Jennifer R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2016
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5187684/
https://ncbi.nlm.nih.gov/pubmed/27911769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604572113
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