Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye

Here we report multiple lines of evidence for a comprehensive model of energy metabolism in the vertebrate eye. Metabolic flux, locations of key enzymes, and our finding that glucose enters mouse and zebrafish retinas mostly through photoreceptors support a conceptually new model for retinal metabol...

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Vydáno v:eLife
Hlavní autoři: Kanow, Mark A, Giarmarco, Michelle M, Jankowski, Connor SR, Tsantilas, Kristine, Engel, Abbi L, Du, Jianhai, Linton, Jonathan D, Farnsworth, Christopher C, Sloat, Stephanie R, Rountree, Austin, Sweet, Ian R, Lindsay, Ken J, Parker, Edward D, Brockerhoff, Susan E, Sadilek, Martin, Chao, Jennifer R, Hurley, James B
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2017
Témata:
Biochemistry and Chemical Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617631/
https://ncbi.nlm.nih.gov/pubmed/28901286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.28899
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