The Importance of an In-depth Study of Immunoglobulin Gene Rearrangements When Ascertaining the Clonal Relationship between Concomitant Chronic Lymphocytic Leukemia and Multiple Myeloma

Chronic lymphocytic leukemia (CLL) and multiple myeloma (MM) are hematological disorders that occur at different stages of B-cell development. It has been shown that CLL B-cells can differentiate into plasma cells in vitro and in vivo. CLL is the most frequent adult leukemia in the western world. It...

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Vydáno v:Front Immunol
Hlavní autoři: Trudel, Stéphanie, Ghamlouch, Hussein, Dremaux, Julie, Delette, Caroline, Harrivel, Véronique, Marolleau, Jean-Pierre, Gubler, Brigitte
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2016
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5187371/
https://ncbi.nlm.nih.gov/pubmed/28082975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00625
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