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Clonal Immunoglobulin against Lysolipids in the Origin of Myeloma

Antigen-driven selection has been implicated in the pathogenesis of monoclonal gammopathies. Patients with Gaucher’s disease have an increased risk of monoclonal gammopathies. Here we show that the clonal immunoglobulin in patients with Gaucher’s disease and in mouse models of Gaucher’s disease–asso...

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Detalhes bibliográficos
Publicado no:N Engl J Med
Main Authors: Nair, Shiny, Branagan, Andrew R., Liu, Jun, Boddupalli, Chandra Sekhar, Mistry, Pramod K., Dhodapkar, Madhav V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4804194/
https://ncbi.nlm.nih.gov/pubmed/26863356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1508808
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