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Clonal Immunoglobulin against Lysolipids in the Origin of Myeloma
Antigen-driven selection has been implicated in the pathogenesis of monoclonal gammopathies. Patients with Gaucher’s disease have an increased risk of monoclonal gammopathies. Here we show that the clonal immunoglobulin in patients with Gaucher’s disease and in mouse models of Gaucher’s disease–asso...
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| Pubblicato in: | N Engl J Med |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4804194/ https://ncbi.nlm.nih.gov/pubmed/26863356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1508808 |
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