Antigen-mediated regulation in monoclonal gammopathies and myeloma

A role for antigen-driven stimulation has been proposed in the pathogenesis of monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM) based largely on the binding properties of monoclonal Ig. However, insights into antigen binding to clonal B cell receptors and in vivo r...

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Foilsithe in:JCI Insight
Main Authors: Nair, Shiny, Sng, Joel, Boddupalli, Chandra Sekhar, Seckinger, Anja, Chesi, Marta, Fulciniti, Mariateresa, Zhang, Lin, Rauniyar, Navin, Lopez, Michael, Neparidze, Natalia, Parker, Terri, Munshi, Nikhil C., Sexton, Rachael, Barlogie, Bart, Orlowski, Robert, Bergsagel, Leif, Hose, Dirk, Flavell, Richard A., Mistry, Pramod K., Meffre, Eric, Dhodapkar, Madhav V.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2018
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931125/
https://ncbi.nlm.nih.gov/pubmed/29669929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98259
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