The Importance of an In-depth Study of Immunoglobulin Gene Rearrangements When Ascertaining the Clonal Relationship between Concomitant Chronic Lymphocytic Leukemia and Multiple Myeloma

Chronic lymphocytic leukemia (CLL) and multiple myeloma (MM) are hematological disorders that occur at different stages of B-cell development. It has been shown that CLL B-cells can differentiate into plasma cells in vitro and in vivo. CLL is the most frequent adult leukemia in the western world. It...

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發表在:Front Immunol
Main Authors: Trudel, Stéphanie, Ghamlouch, Hussein, Dremaux, Julie, Delette, Caroline, Harrivel, Véronique, Marolleau, Jean-Pierre, Gubler, Brigitte
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2016
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5187371/
https://ncbi.nlm.nih.gov/pubmed/28082975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00625
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