The Fab Fragment of a Human Anti-Siglec-9 Monoclonal Antibody Suppresses LPS-Induced Inflammatory Responses in Human Macrophages

Sepsis is a major cause of death for hospitalized patients and is characterized by massive overreaction of immune responses to invading pathogens which is mediated by cytokines. For decades, there has been no effective treatment for sepsis. Sialic acid-binding, Ig-like lectin-9 (Siglec-9), is an imm...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Chu, Sasa, Zhu, Xuhui, You, Na, Zhang, Wei, Zheng, Feng, Cai, Binggang, Zhou, Tingting, Wang, Yiwen, Sun, Qiannan, Yang, Zhiguo, Zhang, Xin, Wang, Changjun, Nie, Shinan, Zhu, Jin, Wang, Maorong
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5183739/
https://ncbi.nlm.nih.gov/pubmed/28082984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00649
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