A Human Anti-Toll Like Receptor 4 Fab Fragment Inhibits Lipopolysaccharide-Induced Pro-Inflammatory Cytokines Production in Macrophages

The results of clinical and experimental studies suggest that endotoxin/toll-like receptor 4 (TLR4)-mediated proinflammatory and profibrotic signaling activation is critical in the development of hepatic fibrosis. However, studies examining the role of specific TLR4 inhibitor are still lacking. The...

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Publicado en:PLoS One
Main Authors: Wang, Maorong, Zheng, Wenkai, Zhu, Xuhui, Xu, Jing, Cai, Binggang, Zhang, Yiqing, Zheng, Feng, Zhou, Linfu, Yang, Zhiguo, Zhang, Xin, Wang, Changjun, Nie, Shinan, Zhu, Jin
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718644/
https://ncbi.nlm.nih.gov/pubmed/26785354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146856
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