The Fab Fragment of a Humanized Anti-Toll Like Receptor 4 (TLR4) Monoclonal Antibody Reduces the Lipopolysaccharide Response via TLR4 in Mouse Macrophages

Lipopolysaccharides (LPS) can induce acute inflammation, sepsis, or chronic inflammatory disorders through the Toll receptor 4 (TLR4) signaling pathway. The TLR4/MD2 (myeloid differentiation protein 2) complex plays a major role in the immune response to LPS. However, there is not a good method to s...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Cai, Binggang, Wang, Maorong, Zhu, Xuhui, Xu, Jing, Zheng, Wenkai, Zhang, Yiqing, Zheng, Feng, Feng, Zhenqing, Zhu, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632812/
https://ncbi.nlm.nih.gov/pubmed/26512658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161025502
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