The Fab Fragment of a Human Anti-Siglec-9 Monoclonal Antibody Suppresses LPS-Induced Inflammatory Responses in Human Macrophages

Sepsis is a major cause of death for hospitalized patients and is characterized by massive overreaction of immune responses to invading pathogens which is mediated by cytokines. For decades, there has been no effective treatment for sepsis. Sialic acid-binding, Ig-like lectin-9 (Siglec-9), is an imm...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Chu, Sasa, Zhu, Xuhui, You, Na, Zhang, Wei, Zheng, Feng, Cai, Binggang, Zhou, Tingting, Wang, Yiwen, Sun, Qiannan, Yang, Zhiguo, Zhang, Xin, Wang, Changjun, Nie, Shinan, Zhu, Jin, Wang, Maorong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5183739/
https://ncbi.nlm.nih.gov/pubmed/28082984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00649
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