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AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway
The AMP-activated protein kinase (AMPK) activator 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) modulates cellular energy metabolism, and promotes mitochondrial proliferation and apoptosis. Previous studies have shown that AICAR has anticancer effects in various cancers, however the roles of...
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| 出版年: | Int J Oncol |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
D.A. Spandidos
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5182012/ https://ncbi.nlm.nih.gov/pubmed/27878239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2016.3775 |
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