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Antitumor effect of YM155, a novel small-molecule survivin suppressant, via mitochondrial apoptosis in human MFH/UPS

Survivin is a member of the inhibitor of apoptosis family, which is known to inhibit mitochondrial apoptosis. Survivin is highly expressed in cancers and plays an important role in cancer cell survival, and increased survivin expression is an unfavorable prognostic marker in cancer patients. YM155,...

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Publicat a:Int J Oncol
Autors principals: MINODA, MASAYA, KAWAMOTO, TERUYA, UEHA, TAKESHI, KAMATA, ETSUKO, MORISHITA, MASAYUKI, HARADA, RISA, TODA, MITSUNORI, ONISHI, YASUO, HARA, HITOMI, KUROSAKA, MASAHIRO, AKISUE, TOSHIHIRO
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532197/
https://ncbi.nlm.nih.gov/pubmed/26166250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2015.3077
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