Antitumor effect of YM155, a novel small-molecule survivin suppressant, via mitochondrial apoptosis in human MFH/UPS

Survivin is a member of the inhibitor of apoptosis family, which is known to inhibit mitochondrial apoptosis. Survivin is highly expressed in cancers and plays an important role in cancer cell survival, and increased survivin expression is an unfavorable prognostic marker in cancer patients. YM155,...

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Pubblicato in:Int J Oncol
Autori principali: MINODA, MASAYA, KAWAMOTO, TERUYA, UEHA, TAKESHI, KAMATA, ETSUKO, MORISHITA, MASAYUKI, HARADA, RISA, TODA, MITSUNORI, ONISHI, YASUO, HARA, HITOMI, KUROSAKA, MASAHIRO, AKISUE, TOSHIHIRO
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2015
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4532197/
https://ncbi.nlm.nih.gov/pubmed/26166250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2015.3077
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