AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway

The AMP-activated protein kinase (AMPK) activator 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) modulates cellular energy metabolism, and promotes mitochondrial proliferation and apoptosis. Previous studies have shown that AICAR has anticancer effects in various cancers, however the roles of...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Int J Oncol
मुख्य लेखकों: Morishita, Masayuki, Kawamoto, Teruya, Hara, Hitomi, Onishi, Yasuo, Ueha, Takeshi, Minoda, Masaya, Katayama, Etsuko, Takemori, Toshiyuki, Fukase, Naomasa, Kurosaka, Masahiro, Kuroda, Ryosuke, Akisue, Toshihiro
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: D.A. Spandidos 2016
विषय:
Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5182012/
https://ncbi.nlm.nih.gov/pubmed/27878239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2016.3775
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