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AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway
The AMP-activated protein kinase (AMPK) activator 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) modulates cellular energy metabolism, and promotes mitochondrial proliferation and apoptosis. Previous studies have shown that AICAR has anticancer effects in various cancers, however the roles of...
Enregistré dans:
| Publié dans: | Int J Oncol |
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| Auteurs principaux: | , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
D.A. Spandidos
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5182012/ https://ncbi.nlm.nih.gov/pubmed/27878239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2016.3775 |
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