Strain Prioritization and Genome Mining for Enediyne Natural Products

The enediyne family of natural products has had a profound impact on modern chemistry, biology, and medicine, and yet only 11 enediynes have been structurally characterized to date. Here we report a genome survey of 3,400 actinomycetes, identifying 81 strains that harbor genes encoding the enediyne...

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Detalles Bibliográficos
Publicado en:mBio
Main Authors: Yan, Xiaohui, Ge, Huiming, Huang, Tingting, Hindra, Yang, Dong, Teng, Qihui, Crnovčić, Ivana, Li, Xiuling, Rudolf, Jeffrey D., Lohman, Jeremy R., Gansemans, Yannick, Zhu, Xiangcheng, Huang, Yong, Zhao, Li-Xing, Jiang, Yi, Van Nieuwerburgh, Filip, Rader, Christoph, Duan, Yanwen, Shen, Ben
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5181780/
https://ncbi.nlm.nih.gov/pubmed/27999165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02104-16
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