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Glucocerebrosidase modulates cognitive and motor activities in murine models of Parkinson’s disease

Mutations in GBA1, the gene encoding glucocerebrosidase, are associated with an enhanced risk of developing synucleinopathies such as Parkinson’s disease (PD) and dementia with Lewy bodies. A higher prevalence and increased severity of motor and non-motor symptoms is observed in PD patients harborin...

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Dades bibliogràfiques
Publicat a:Hum Mol Genet
Autors principals: Rockenstein, Edward, Clarke, Jennifer, Viel, Catherine, Panarello, Nicholas, Treleaven, Christopher M., Kim, Changyoun, Spencer, Brian, Adame, Anthony, Park, Hyejung, Dodge, James C., Cheng, Seng H., Shihabuddin, Lamya S., Masliah, E., Sardi, S. Pablo
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5181635/
https://ncbi.nlm.nih.gov/pubmed/27126635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw124
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