Genetic ablation of IP(3) receptor 2 increases cytokines and decreases survival of SOD1(G93A) mice

Amyotrophic lateral sclerosis (ALS) is a devastating progressive neurodegenerative disease characterized by the selective death of motor neurons. Disease pathophysiology is complex and not yet fully understood. Higher gene expression of the inositol 1,4,5-trisphosphate receptor 2 gene (ITPR2), encod...

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發表在:Hum Mol Genet
Main Authors: Staats, Kim A., Humblet-Baron, Stephanie, Bento-Abreu, Andre, Scheveneels, Wendy, Nikolaou, Alexandros, Deckers, Kato, Lemmens, Robin, Goris, An, Van Ginderachter, Jo A., Van Damme, Philip, Hisatsune, Chihiro, Mikoshiba, Katsuhiko, Liston, Adrian, Robberecht, Wim, Van Den Bosch, Ludo
格式: Artigo
語言:Inglês
出版: Oxford University Press 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179944/
https://ncbi.nlm.nih.gov/pubmed/27378687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw190
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