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Conditional deletion of Id2 or Notch1 in oligodendrocyte progenitor cells does not ameliorate disease outcome in SOD1(G93A) mice

Oligodendrocytes are essential for structural and trophic support of motor axons. Their impairment has been implicated in amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder of motor neurons. Oligodendrocyte progenitor cells fail to differentiate into mature oligodendrocytes and thereb...

詳細記述

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書誌詳細
出版年:Neurobiol Aging
主要な著者: Eykens, Caroline, Nonneman, Annelies, Jensen, Cathy, Iavarone, Antonio, Van Damme, Philip, Van Den Bosch, Ludo, Robberecht, Wim
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5998381/
https://ncbi.nlm.nih.gov/pubmed/29689424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2018.03.026
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