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Rapamycin increases survival in ALS mice lacking mature lymphocytes

BACKGROUND: Amyotrophic Lateral Sclerosis (ALS) is a devastating progressive neurodegenerative disease. Disease pathophysiology is complex and not yet fully understood, but is proposed to include the accumulation of misfolded proteins, as aggregates are present in spinal cords from ALS patients and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Staats, Kim A, Hernandez, Sara, Schönefeldt, Susann, Bento-Abreu, André, Dooley, James, Van Damme, Philip, Liston, Adrian, Robberecht, Wim, Van Den Bosch, Ludo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847677/
https://ncbi.nlm.nih.gov/pubmed/24025516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-8-31
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