Rapamycin increases survival in ALS mice lacking mature lymphocytes

BACKGROUND: Amyotrophic Lateral Sclerosis (ALS) is a devastating progressive neurodegenerative disease. Disease pathophysiology is complex and not yet fully understood, but is proposed to include the accumulation of misfolded proteins, as aggregates are present in spinal cords from ALS patients and...

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Hlavní autoři: Staats, Kim A, Hernandez, Sara, Schönefeldt, Susann, Bento-Abreu, André, Dooley, James, Van Damme, Philip, Liston, Adrian, Robberecht, Wim, Van Den Bosch, Ludo
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Short Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3847677/
https://ncbi.nlm.nih.gov/pubmed/24025516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-8-31
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