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Identification of plexin A4 as a novel clusterin receptor links two Alzheimer’s disease risk genes
Although abundant genetic and biochemical evidence strongly links Clusterin (CLU) to Alzheimer disease (AD) pathogenesis, the receptor for CLU within the adult brain is currently unknown. Using unbiased approaches, we identified Plexin A4 (PLXNA4) as a novel, high-affinity receptor for CLU in the ad...
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| Gepubliceerd in: | Hum Mol Genet |
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| Hoofdauteurs: | , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5179943/ https://ncbi.nlm.nih.gov/pubmed/27378688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw188 |
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