Identification of plexin A4 as a novel clusterin receptor links two Alzheimer’s disease risk genes

Although abundant genetic and biochemical evidence strongly links Clusterin (CLU) to Alzheimer disease (AD) pathogenesis, the receptor for CLU within the adult brain is currently unknown. Using unbiased approaches, we identified Plexin A4 (PLXNA4) as a novel, high-affinity receptor for CLU in the ad...

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Detaylı Bibliyografya
Yayımlandı:Hum Mol Genet
Asıl Yazarlar: Kang, Silvia S., Kurti, Aishe, Wojtas, Aleksandra, Baker, Kelsey E., Liu, Chia-Chen, Kanekiyo, Takahisa, Deming, Yuetiva, Cruchaga, Carlos, Estus, Steven, Bu, Guojun, Fryer, John D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2016
Konular:
Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179943/
https://ncbi.nlm.nih.gov/pubmed/27378688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw188
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