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A Novel Sensitive Method to Measure Catechol-O-Methyltransferase Activity Unravels the Presence of This Activity in Extracellular Vesicles Released by Rat Hepatocytes

There is a clear need for drug treatments to be selected according to the characteristics of an individual patient, in order to improve efficacy and reduce the number and severity of adverse drug reactions. One of the main enzymes to take into account in pharmacogenomics is catechol O-methyltransfer...

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Veröffentlicht in:Front Pharmacol
Hauptverfasser: Casal, Enriqueta, Palomo, Laura, Cabrera, Diana, Falcon-Perez, Juan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179529/
https://ncbi.nlm.nih.gov/pubmed/28066248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00501
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