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Hepatocyte-secreted extracellular vesicles modify blood metabolome and endothelial function by an arginase-dependent mechanism

Hepatocytes release extracellular vesicles (EVs) loaded with signaling molecules and enzymes into the bloodstream. Although the importance of EVs in the intercellular communication is already recognized, the metabolic impact of the enzymes carried by these vesicles is still unclear. We evaluated the...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Royo, Felix, Moreno, Laura, Mleczko, Justyna, Palomo, Laura, Gonzalez, Esperanza, Cabrera, Diana, Cogolludo, Angel, Vizcaino, Francisco Perez, van-Liempd, Sebastiaan, Falcon-Perez, Juan M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314384/
https://ncbi.nlm.nih.gov/pubmed/28211494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42798
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