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Hepatocyte-secreted extracellular vesicles modify blood metabolome and endothelial function by an arginase-dependent mechanism
Hepatocytes release extracellular vesicles (EVs) loaded with signaling molecules and enzymes into the bloodstream. Although the importance of EVs in the intercellular communication is already recognized, the metabolic impact of the enzymes carried by these vesicles is still unclear. We evaluated the...
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Опубликовано в: : | Sci Rep |
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Главные авторы: | , , , , , , , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Nature Publishing Group
2017
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5314384/ https://ncbi.nlm.nih.gov/pubmed/28211494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42798 |
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