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Hepatocyte-secreted extracellular vesicles modify blood metabolome and endothelial function by an arginase-dependent mechanism

Hepatocytes release extracellular vesicles (EVs) loaded with signaling molecules and enzymes into the bloodstream. Although the importance of EVs in the intercellular communication is already recognized, the metabolic impact of the enzymes carried by these vesicles is still unclear. We evaluated the...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Royo, Felix, Moreno, Laura, Mleczko, Justyna, Palomo, Laura, Gonzalez, Esperanza, Cabrera, Diana, Cogolludo, Angel, Vizcaino, Francisco Perez, van-Liempd, Sebastiaan, Falcon-Perez, Juan M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314384/
https://ncbi.nlm.nih.gov/pubmed/28211494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42798
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