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Hepatocyte-secreted extracellular vesicles modify blood metabolome and endothelial function by an arginase-dependent mechanism

Hepatocytes release extracellular vesicles (EVs) loaded with signaling molecules and enzymes into the bloodstream. Although the importance of EVs in the intercellular communication is already recognized, the metabolic impact of the enzymes carried by these vesicles is still unclear. We evaluated the...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Royo, Felix, Moreno, Laura, Mleczko, Justyna, Palomo, Laura, Gonzalez, Esperanza, Cabrera, Diana, Cogolludo, Angel, Vizcaino, Francisco Perez, van-Liempd, Sebastiaan, Falcon-Perez, Juan M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314384/
https://ncbi.nlm.nih.gov/pubmed/28211494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42798
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