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A Novel Sensitive Method to Measure Catechol-O-Methyltransferase Activity Unravels the Presence of This Activity in Extracellular Vesicles Released by Rat Hepatocytes

There is a clear need for drug treatments to be selected according to the characteristics of an individual patient, in order to improve efficacy and reduce the number and severity of adverse drug reactions. One of the main enzymes to take into account in pharmacogenomics is catechol O-methyltransfer...

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Pubblicato in:Front Pharmacol
Autori principali: Casal, Enriqueta, Palomo, Laura, Cabrera, Diana, Falcon-Perez, Juan M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179529/
https://ncbi.nlm.nih.gov/pubmed/28066248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00501
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