Loading...
Hypoxia drives the transition of human dermal fibroblasts to a myofibroblast-like phenotype via the TGF-β1/Smad3 pathway
Keloids, partially considered as benign tumors, are characterized by the overgrowth of fibrosis beyond the boundaries of the wound and are regulated mainly by transforming growth factor (TGF)-β1, which induces the transition of fibroblasts to myofibroblasts. Hypoxia is an important driving force in...
Saved in:
| Published in: | Int J Mol Med |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
D.A. Spandidos
2017
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5179176/ https://ncbi.nlm.nih.gov/pubmed/27909731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2016.2816 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|