Fenofibrate Reduces the Asthma-Related Fibroblast-To-Myofibroblast Transition by TGF-Β/Smad2/3 Signaling Attenuation and Connexin 43-Dependent Phenotype Destabilization

The activation of human bronchial fibroblasts by transforming growth factor-β(1) (TGF-β(1)) leads to the formation of highly contractile myofibroblasts in the process of the fibroblast–myofibroblast transition (FMT). This process is crucial for subepithelial fibrosis and bronchial wall remodeling in...

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發表在:Int J Mol Sci
Main Authors: Paw, Milena, Wnuk, Dawid, Kądziołka, Dominika, Sęk, Aleksandra, Lasota, Sławomir, Czyż, Jarosław, Madeja, Zbigniew, Michalik, Marta
格式: Artigo
語言:Inglês
出版: MDPI 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6163263/
https://ncbi.nlm.nih.gov/pubmed/30158495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19092571
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