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The Mitochondrial Permeability Transition Pore Regulator Cyclophilin D Exhibits Tissue-Specific Control of Metabolic Homeostasis

The mitochondrial permeability transition pore (mPTP) is a key regulator of mitochondrial function that has been implicated in the pathogenesis of metabolic disease. Cyclophilin D (CypD) is a critical regulator that directly binds to mPTP constituents to facilitate the pore opening. We previously fo...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Laker, Rhianna C., Taddeo, Evan P., Akhtar, Yasir N., Zhang, Mei, Hoehn, Kyle L., Yan, Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5179060/
https://ncbi.nlm.nih.gov/pubmed/28005946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167910
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