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Structural Mechanisms of Cyclophilin D-Dependent Control of the Mitochondrial Permeability Transition Pore

BACKGROUND: Opening of the Mitochondrial Permeability Transition pore is the underlying cause of cellular dysfunction during diverse pathological situations. Although this bioenergetic entity has been studied extensively, its molecular componentry is constantly debated. Cyclophilin D is the only uni...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Gutiérrez-Aguilar, Manuel, Baines, Christopher P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430462/
https://ncbi.nlm.nih.gov/pubmed/25445707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2014.11.009
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