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Structural Mechanisms of Cyclophilin D-Dependent Control of the Mitochondrial Permeability Transition Pore
BACKGROUND: Opening of the Mitochondrial Permeability Transition pore is the underlying cause of cellular dysfunction during diverse pathological situations. Although this bioenergetic entity has been studied extensively, its molecular componentry is constantly debated. Cyclophilin D is the only uni...
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Publicado no: | Biochim Biophys Acta |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4430462/ https://ncbi.nlm.nih.gov/pubmed/25445707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2014.11.009 |
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