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Structural Mechanisms of Cyclophilin D-Dependent Control of the Mitochondrial Permeability Transition Pore

BACKGROUND: Opening of the Mitochondrial Permeability Transition pore is the underlying cause of cellular dysfunction during diverse pathological situations. Although this bioenergetic entity has been studied extensively, its molecular componentry is constantly debated. Cyclophilin D is the only uni...

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Publicat a:Biochim Biophys Acta
Autors principals: Gutiérrez-Aguilar, Manuel, Baines, Christopher P.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430462/
https://ncbi.nlm.nih.gov/pubmed/25445707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2014.11.009
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