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LSD1 Histone Demethylase Assays and Inhibition
The lysine-specific demethylase (LSD1) is a flavin-dependent amine oxidase that selectively removes one or two methyl groups from histone H3 at the Lys4 position. Along with histone deacetylases 1 and 2, LSD1 is involved in epigenetically silencing gene expression. LSD1 has been implicated as a pote...
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| Publicado no: | Methods Enzymol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5178825/ https://ncbi.nlm.nih.gov/pubmed/27372757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2016.01.020 |
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