Blocking triggering receptor expressed on myeloid cells-1 attenuates lipopolysaccharide-induced acute lung injury via inhibiting NLRP3 inflammasome activation

Acute lung injury (ALI) is associated with high mortality and uncontrolled inflammation plays a critical role in ALI. TREM-1 is an amplifier of inflammatory response, and is involved in the pathogenesis of many infectious diseases. NLRP3 inflammasome is a member of NLRs family that contributes to AL...

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Publicado no:Sci Rep
Main Authors: Liu, Tian, Zhou, Yong, Li, Ping, Duan, Jia-Xi, Liu, Yong-Ping, Sun, Guo-Ying, Wan, Li, Dong, Liang, Fang, Xiang, Jiang, Jian-Xin, Guan, Cha-Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177963/
https://ncbi.nlm.nih.gov/pubmed/28004759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39473
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