NLRP3 Triggers Attenuate Lipocalin-2 Expression Independent with Inflammasome Activation

Lipocalin-2 (LCN2), a small secretory glycoprotein, is upregulated by toll-like receptor (TLR) signaling in various cells and tissues. LCN2 inhibits bacterial growth by iron sequestration and regulates the innate immune system. Inflammasome activates the inflammatory caspases leading to pyroptosis a...

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Bibliografiske detaljer
Udgivet i:Cells
Main Authors: Ahn, Huijeong, Lee, Gilyoung, Kim, Jeongeun, Park, Jeongho, Kang, Seung Goo, Yoon, Sung-Il, Lee, Eunsong, Lee, Geun-Shik
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305203/
https://ncbi.nlm.nih.gov/pubmed/34359830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10071660
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