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Poly-gamma-glutamic acid from Bacillus subtilis upregulates pro-inflammatory cytokines while inhibiting NLRP3, NLRC4 and AIM2 inflammasome activation

Poly-gamma-glutamic acid (γ-PGA) is a natural, edible and non-toxic polymer synthesized by Bacillus subtilis and is suggested as a safe biomaterial for the use in hydrogels and vaccine adjuvants. However, the effect of γ-PGA on inflammasome activation has not yet been studied in macrophages. Inflamm...

詳細記述

保存先:
書誌詳細
出版年:Cell Mol Immunol
主要な著者: Ahn, Huijeong, Kang, Seung Goo, Yoon, Sung-il, Kim, Pyeung-Hyeun, Kim, Doo, Lee, Geun-Shik
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811673/
https://ncbi.nlm.nih.gov/pubmed/27133472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2016.13
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