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NLRP3 Triggers Attenuate Lipocalin-2 Expression Independent with Inflammasome Activation

Lipocalin-2 (LCN2), a small secretory glycoprotein, is upregulated by toll-like receptor (TLR) signaling in various cells and tissues. LCN2 inhibits bacterial growth by iron sequestration and regulates the innate immune system. Inflammasome activates the inflammatory caspases leading to pyroptosis a...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Ahn, Huijeong, Lee, Gilyoung, Kim, Jeongeun, Park, Jeongho, Kang, Seung Goo, Yoon, Sung-Il, Lee, Eunsong, Lee, Geun-Shik
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305203/
https://ncbi.nlm.nih.gov/pubmed/34359830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10071660
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