Angiotensin II increases glomerular permeability by β-arrestin mediated nephrin endocytosis

Glomerular permeability and subsequent albuminuria are early clinical markers for glomerular injury in hypertensive nephropathy. Albuminuria predicts mortality and cardiovascular morbidity. AT1 receptor blockers protect from albuminuria, cardiovascular morbidity and mortality. A blood pressure indep...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Königshausen, Eva, Zierhut, Ulf M., Ruetze, Martin, Potthoff, Sebastian A., Stegbauer, Johannes, Woznowski, Magdalena, Quack, Ivo, Rump, Lars C., Sellin, Lorenz
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5177899/
https://ncbi.nlm.nih.gov/pubmed/28004760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39513
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