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β-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity
β-Arrestins mediate internalization of plasma membrane receptors. Nephrin, a structural component of the glomerular slit diaphragm, is a single transmembrane spanning receptor and belongs to the family of adhesion molecules. Its mutation causes a hereditary nephrotic syndrome. We report the previous...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1564064/ https://ncbi.nlm.nih.gov/pubmed/16968782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602587103 |
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