Splice variant insertions in the C-terminus impairs YAP’s transactivation domain

The yes-associated protein (YAP) is a key effector of the mammalian Hippo signaling pathway. YAP has eight known alternately spliced isoforms and these are widely expressed across multiple tissues. Variable effects have been ascribed to different YAP isoforms by inducing their expression in cells, b...

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Vydáno v:Biochem Biophys Rep
Hlavní autoři: Finch-Edmondson, Megan L., Strauss, Robyn P., Clayton, Joshua S., Yeoh, George C., Callus, Bernard A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5176130/
https://ncbi.nlm.nih.gov/pubmed/28018981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2016.02.015
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