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Molecular insights into the mechanism of calmodulin inhibition of the EAG1 potassium channel

The human EAG1 potassium channel belongs to the superfamily of KCNH voltage-gated potassium channels that have roles in cardiac repolarization and neuronal excitability. EAG1 is strongly inhibited by Ca(2+)-calmodulin (CaM) through a mechanism that is not understood. We determined the binding proper...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Structure
मुख्य लेखकों: Marques-Carvalho, Maria João, Oppermann, Johannes, Muñoz, Eva, Fernandes, Andreia S., Gabant, Guillaume, Cadene, Martine, Heinemann, Stefan H., Schönherr, Roland, Morais-Cabral, João Henrique
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5176025/
https://ncbi.nlm.nih.gov/pubmed/27618660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.07.020
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