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Molecular insights into the mechanism of calmodulin inhibition of the EAG1 potassium channel
The human EAG1 potassium channel belongs to the superfamily of KCNH voltage-gated potassium channels that have roles in cardiac repolarization and neuronal excitability. EAG1 is strongly inhibited by Ca(2+)-calmodulin (CaM) through a mechanism that is not understood. We determined the binding proper...
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| Publicat a: | Structure |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5176025/ https://ncbi.nlm.nih.gov/pubmed/27618660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.07.020 |
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