The interaction between the Drosophila EAG potassium channel and the protein kinase CaMKII involves an extensive interface at the active site of the kinase.

The Drosophila EAG (dEAG) potassium channel is the founding member of the superfamily of KNCH channels, which are involved in cardiac repolarization, neuronal excitability and cellular proliferation. In flies, dEAG is involved in regulation of neuron firing and assembles with CaMKII to form a comple...

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Veröffentlicht in:J Mol Biol
Hauptverfasser: Castro-Rodrigues, Artur F., Zhao, Yaxian, Fonseca, Fátima, Gabant, Guillaume, Cadene, Martine, Robertson, Gail A., Morais-Cabral, João H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6658111/
https://ncbi.nlm.nih.gov/pubmed/30381148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.10.015
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