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Screening for Non-Pore Binding Modulators of EAG K(+) Channels

Members of the EAG family of voltage gated K(+) channels are involved in several pathophysiological diseases and there has been a great interest in screening for drugs that modulate the activity of these channels. Many drugs have been shown to bind in the pore of these channels blocking ion flux and...

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Dettagli Bibliografici
Pubblicato in:J Biomol Screen
Autori principali: Fernandes, Andreia S., Morais-Cabral, João H., Harley, Carol A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696618/
https://ncbi.nlm.nih.gov/pubmed/26975997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057116636592
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