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Screening for Non-Pore Binding Modulators of EAG K(+) Channels

Members of the EAG family of voltage gated K(+) channels are involved in several pathophysiological diseases and there has been a great interest in screening for drugs that modulate the activity of these channels. Many drugs have been shown to bind in the pore of these channels blocking ion flux and...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Biomol Screen
Päätekijät: Fernandes, Andreia S., Morais-Cabral, João H., Harley, Carol A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696618/
https://ncbi.nlm.nih.gov/pubmed/26975997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057116636592
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