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Inhibition of human ether à go-go potassium channels by Ca(2+)/calmodulin

Intracellular Ca(2+) inhibits voltage-gated potassium channels of the ether à go-go (EAG) family. To identify the underlying molecular mechanism, we expressed the human version hEAG1 in Xenopus oocytes. The channels lost Ca(2+) sensitivity when measured in cell-free membrane patches. However, Ca(2+)...

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Bibliografski detalji
Glavni autori: Schönherr, Roland, Löber, Karsten, Heinemann, Stefan H.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC313935/
https://ncbi.nlm.nih.gov/pubmed/10880439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.13.3263
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