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Inhibition of human ether à go-go potassium channels by Ca(2+)/calmodulin
Intracellular Ca(2+) inhibits voltage-gated potassium channels of the ether à go-go (EAG) family. To identify the underlying molecular mechanism, we expressed the human version hEAG1 in Xenopus oocytes. The channels lost Ca(2+) sensitivity when measured in cell-free membrane patches. However, Ca(2+)...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2000
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC313935/ https://ncbi.nlm.nih.gov/pubmed/10880439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.13.3263 |
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