Aged Muscle Demonstrates Fiber-Type Adaptations in Response to Mechanical Overload, in the Absence of Myofiber Hypertrophy, Independent of Satellite Cell Abundance

Although sarcopenia, age-associated loss of muscle mass and strength, is neither accelerated nor exacerbated by depletion of muscle stem cells, satellite cells, we hypothesized that adaptation in sarcopenic muscle would be compromised. To test this hypothesis, we depleted satellite cells with tamoxi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Gerontol A Biol Sci Med Sci
Prif Awduron: Lee, Jonah D., Fry, Christopher S., Mula, Jyothi, Kirby, Tyler J., Jackson, Janna R., Liu, Fujun, Yang, Lin, Dupont-Versteegden, Esther E., McCarthy, John J., Peterson, Charlotte A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2016
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175449/
https://ncbi.nlm.nih.gov/pubmed/25878030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glv033
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