Aged Muscle Demonstrates Fiber-Type Adaptations in Response to Mechanical Overload, in the Absence of Myofiber Hypertrophy, Independent of Satellite Cell Abundance

Although sarcopenia, age-associated loss of muscle mass and strength, is neither accelerated nor exacerbated by depletion of muscle stem cells, satellite cells, we hypothesized that adaptation in sarcopenic muscle would be compromised. To test this hypothesis, we depleted satellite cells with tamoxi...

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Bibliografski detalji
Izdano u:J Gerontol A Biol Sci Med Sci
Glavni autori: Lee, Jonah D., Fry, Christopher S., Mula, Jyothi, Kirby, Tyler J., Jackson, Janna R., Liu, Fujun, Yang, Lin, Dupont-Versteegden, Esther E., McCarthy, John J., Peterson, Charlotte A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2016
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Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175449/
https://ncbi.nlm.nih.gov/pubmed/25878030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glv033
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