Differential requirement for satellite cells during overload-induced muscle hypertrophy in growing versus mature mice

Abstract Background Pax7+ satellite cells are required for skeletal muscle fiber growth during post-natal development in mice. Satellite cell-mediated myonuclear accretion also appears to persist into early adulthood. Given the important role of satellite cells during muscle development, we hypothes...

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Detalhes bibliográficos
Main Authors: Kevin A. Murach, Sarah H. White, Yuan Wen, Angel Ho, Esther E. Dupont-Versteegden, John J. McCarthy, Charlotte A. Peterson
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-07-01
Colecção:Skeletal Muscle
Assuntos:
Pax7
Synergist ablation
Regeneration
Fiber splitting
Development
Muscle hypertrophy
Acesso em linha:http://link.springer.com/article/10.1186/s13395-017-0132-z
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