Aged Muscle Demonstrates Fiber-Type Adaptations in Response to Mechanical Overload, in the Absence of Myofiber Hypertrophy, Independent of Satellite Cell Abundance

Although sarcopenia, age-associated loss of muscle mass and strength, is neither accelerated nor exacerbated by depletion of muscle stem cells, satellite cells, we hypothesized that adaptation in sarcopenic muscle would be compromised. To test this hypothesis, we depleted satellite cells with tamoxi...

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Detalhes bibliográficos
Publicado no:J Gerontol A Biol Sci Med Sci
Main Authors: Lee, Jonah D., Fry, Christopher S., Mula, Jyothi, Kirby, Tyler J., Jackson, Janna R., Liu, Fujun, Yang, Lin, Dupont-Versteegden, Esther E., McCarthy, John J., Peterson, Charlotte A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175449/
https://ncbi.nlm.nih.gov/pubmed/25878030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glv033
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