IcmF and DotU Are Required for Optimal Effector Translocation and Trafficking of the Legionella pneumophila Vacuole

The gram-negative bacterium Legionella pneumophila causes a severe form of pneumonia called Legionnaires' disease, characterized by bacterial replication within alveolar macrophages. Prior to intracellular replication, the vacuole harboring the bacterium must first escape trafficking to the hos...

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Hlavní autoři: VanRheenen, Susan M., Duménil, Guillaume, Isberg, Ralph R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC517542/
https://ncbi.nlm.nih.gov/pubmed/15385501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.10.5972-5982.2004
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