IcmF and DotU Are Required for Optimal Effector Translocation and Trafficking of the Legionella pneumophila Vacuole

The gram-negative bacterium Legionella pneumophila causes a severe form of pneumonia called Legionnaires' disease, characterized by bacterial replication within alveolar macrophages. Prior to intracellular replication, the vacuole harboring the bacterium must first escape trafficking to the host lys...

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Bibliografische Detailangaben

Veröffentlicht in:	Infect Immun
Hauptverfasser:	VanRheenen, Susan M., Duménil, Guillaume, Isberg, Ralph R.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2004
Schlagworte:	Molecular Pathogenesis
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC517542/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15385501/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.10.5972-5982.2004
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