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IcmF and DotU Are Required for Optimal Effector Translocation and Trafficking of the Legionella pneumophila Vacuole

The gram-negative bacterium Legionella pneumophila causes a severe form of pneumonia called Legionnaires' disease, characterized by bacterial replication within alveolar macrophages. Prior to intracellular replication, the vacuole harboring the bacterium must first escape trafficking to the hos...

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Detalhes bibliográficos
Main Authors: VanRheenen, Susan M., Duménil, Guillaume, Isberg, Ralph R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC517542/
https://ncbi.nlm.nih.gov/pubmed/15385501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.10.5972-5982.2004
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