Legionella pneumophila DotU and IcmF Are Required for Stability of the Dot/Icm Complex

Legionella pneumophila utilizes a type IV secretion system (T4SS) encoded by 26 dot/icm genes to replicate inside host cells and cause disease. In contrast to all other L. pneumophila dot/icm genes, dotU and icmF have homologs in a wide variety of gram-negative bacteria, none of which possess a T4SS...

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Bibliographic Details
Main Authors: Sexton, Jessica A., Miller, Jennifer L., Yoneda, Aki, Kehl-Fie, Thomas E., Vogel, Joseph P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Molecular Pathogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC517559/
https://ncbi.nlm.nih.gov/pubmed/15385502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.10.5983-5992.2004
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