Chtop (Chromatin target of Prmt1) auto-regulates its expression level via intron retention and nonsense-mediated decay of its own mRNA

Chtop (chromatin target of Prmt1) regulates various aspects of gene expression including transcription and mRNA export. Despite these important functions, the regulatory mechanism underlying Chtop expression remains undetermined. Using Chtop-expressing human cell lines, we demonstrate that Chtop exp...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Izumikawa, Keiichi, Yoshikawa, Harunori, Ishikawa, Hideaki, Nobe, Yuko, Yamauchi, Yoshio, Philipsen, Sjaak, Simpson, Richard J, Isobe, Toshiaki, Takahashi, Nobuhiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Molecular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5175361/
https://ncbi.nlm.nih.gov/pubmed/27683223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw831
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